Related Experiment Video
Updated: Jun 28, 2025

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
Published on: November 3, 2015
Leveraging elasticity of blood stenosis to detect the role of a non-Newtonian flow midst an arterial tube: Mazumdar
A M Awad1, Kh S Mekheimer2, S A Elkilany1
1Mathematics Department, Faculty of Science, Kafrelsheikh University, Kafrelsheikh, Egypt.
This study models blood flow through narrowed arteries (stenosis), a risk factor for COVID-19. Increased artery wall elasticity was found to improve blood flow, with findings comparable to existing research.
Area of Science:
- Biomedical Engineering
- Fluid Dynamics
- Cardiovascular Science
Background:
- Blood stenosis is a significant health risk and a symptom of COVID-19.
- Understanding blood flow dynamics in stenosed arteries is crucial for patient outcomes.
Purpose of the Study:
- To investigate blood flow in stenosed arteries considering blood clots and arterial wall elasticity.
- To compare the efficacy of the Rubinow & Keller and Mazumdar models for arterial elasticity.
Main Methods:
- Utilized the Herschel-Bulkley model for blood as a yield stress fluid.
- Employed Navier-Stokes equations for mathematical simulation.
- Incorporated Rubinow & Keller and Mazumdar models to simulate arterial wall elasticity.
Main Results:
- Demonstrated that increased arterial wall elasticity parameters facilitate blood flow through stenosis.
- Results for non-stenosed arteries align with established research by Vajravelu et al.
- Highlighted the importance of studying non-Newtonian fluid flow phenomena in cardiovascular contexts.
Conclusions:
- Arterial wall elasticity plays a key role in mitigating blood flow obstruction in stenosis.
- The Herschel-Bulkley model effectively simulates blood flow under these conditions.
- Further research into non-Newtonian fluid dynamics is warranted for cardiovascular health.
More Related Videos
11:00Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section
Published on: July 19, 2016
13:07Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Related Concept Videos
Steady, Laminar Flow in Circular Tubes
Autoregulation of Blood Flow
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....
Navier–Stokes Equations
Typical Model Studies
Newtonian Fluid: Problem Solving
A velocity gradient forms within the fluid when a Newtonian fluid is placed between two parallel plates, with...
Laminar and Turbulent Flow