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Reactive Vapor Deposition of Conjugated Polymer Films on Arbitrary Substrates
Published on: January 17, 2018
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Scaffold-Based Poly(Vinylidene Fluoride) and Its Copolymers: Materials, Fabrication Methods, Applications, and
Wenbin Sun1, Chuang Gao1, Huazhen Liu1,2
1School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, China.
ACS Biomaterials Science & Engineering
|April 15, 2024
Summary
Poly(vinylidene fluoride) (PVDF) scaffolds offer electrical stimulation for enhanced tissue repair. This review details PVDF copolymers, fabrication methods, and applications in bone, nerve, muscle, skin, and blood vessel regeneration.
Area of Science:
- Biomaterials Science
- Tissue Engineering
- Polymer Science
Background:
- Tissue engineering utilizes grafts to regenerate damaged tissues, requiring scaffolds for cellular support.
- Piezoelectric scaffolds provide electrical stimulation, accelerating tissue repair without external power.
- Poly(vinylidene fluoride) (PVDF) and its copolymers are leading piezoelectric polymers in biomedical applications.
Purpose of the Study:
- To provide a comprehensive overview of PVDF and its copolymers for tissue engineering scaffolds.
- To discuss the role of fillers in enhancing scaffold properties.
- To outline fabrication methods and applications of PVDF-based scaffolds.
Main Methods:
- Review of literature on PVDF and copolymer synthesis.
- Analysis of scaffold fabrication techniques (3D printing, electrospinning, etc.).
- Examination of PVDF applications in various tissue types.
Main Results:
- PVDF and its copolymers demonstrate significant piezoelectric properties.
- Fillers can improve piezoelectric output, bioactivity, and mechanical strength of scaffolds.
- Scaffold-based PVDF shows promise in regenerating bone, nerve, muscle, skin, and blood vessels.
Conclusions:
- PVDF-based scaffolds are versatile tools in tissue engineering.
- Further research into fabrication and application strategies is needed.
- PVDF holds significant potential for future advancements in regenerative medicine.
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