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Published on: April 15, 2021
The natural history of celiac artery aneurysms
Molly Ratner1, C Austen Hartwell2, Jason Zhang1
1Division of Vascular and Endovascular Surgery, Department of Surgery, New York University Langone Medical Center, New York, NY, USA.
Insights
Most celiac artery aneurysms (CAAs) remain stable without rupture or symptoms. Age under 70 may increase growth risk, supporting conservative management for smaller CAAs.
Area of Science:
- Vascular Surgery
- Radiology
- Gastroenterology
Background:
- Celiac artery aneurysms (CAAs) are rare vascular conditions.
- Limited data exists on the natural history of untreated CAAs.
- Existing research often focuses on symptomatic or large aneurysms requiring intervention.
Purpose of the Study:
- To document the natural history of celiac artery aneurysms (CAAs).
- To understand the behavior and growth patterns of untreated CAAs.
- To evaluate factors influencing CAA progression.
Main Methods:
- Retrospective analysis of patients diagnosed with CAA via CT imaging (2015-2019).
- Inclusion of radiologic, demographic, and clinical follow-up data.
- Primary endpoint: mean growth rate of CAAs.
Main Results:
- 76 patients included; 86.8% male, mean age 69.8 years.
- Mean CAA diameter 15.4 mm; 76.3% saccular.
- 35.6% of CAAs enlarged over mean follow-up of 25.2 months; no ruptures or symptoms reported. Age <70 associated with growth risk.
Conclusions:
- The majority of CAAs demonstrate stable size and benign behavior.
- No symptoms or ruptures observed during clinical follow-up.
- Conservative management for CAAs <2 cm appears appropriate based on findings.
Abstract:
ObjectivesThe goal of this study was to document the natural history of celiac artery aneurysms (CAAs).BackgroundCeliac artery aneurysms are rare. Existing literature is skewed towards outcomes after intervention of large, symptomatic aneurysms but the behavior of untreated CAAs is poorly understood.MethodsThis is a single institution, retrospective analysis of patients with CAA diagnosed by CT imaging (2015-2019) identified through an institutional radiology database. Radiologic, demographic, and follow-up data were analyzed. The primary endpoint was the mean growth rate of CAAs.ResultsOf the 76 patients included, 86.8% were men with a mean age at presentation of 69.8 years. The mean CAA diameter on index imaging was 15.4 +/- 3.8 mm (range, 7-30 mm). All were classified as true aneurysms and 76.3% were saccular. All patients had clinical follow-up with mean follow-up 31.2 months +/- 21.6 months. No patient developed symptoms or rupture. The mean radiological follow-up among 45 patients was 25.2 +/- 16.8 months. Over this period, 16 CAAs (35.6%) enlarged, while 29 (64.4%) remained stable. One patient (1.3%) underwent intervention for increasing size in the setting of a chronic dissection. On multivariate analysis, age <70 was significantly associated with increased risk of aneurysm growth.ConclusionsIn this institutional review of patients with CAAs, the majority of aneurysms remained stable in size, with no patients developing symptoms or rupture over clinical follow-up. Given the observed benign behavior of these aneurysms, guidelines that suggest conservative management of CAAs less than 2 cm seems appropriate.
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