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Performance of ChatGPT on Factual Knowledge Questions Regarding Clinical Pharmacy.

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ChatGPT demonstrates high accuracy and reproducibility in answering clinical pharmacy knowledge questions, outperforming pharmacists. This suggests its potential as a valuable resource for pharmacy professionals seeking reliable information.

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Area of Science:

  • Pharmacy
  • Artificial Intelligence
  • Medical Education

Background:

  • Large language models like ChatGPT are increasingly integrated into various professional fields.
  • Previous studies have assessed ChatGPT's performance on general medical examinations.
  • The specific utility of ChatGPT for clinical pharmacy knowledge remains underexplored.

Purpose of the Study:

  • To evaluate the accuracy, concordance, substantiation quality, and reproducibility of ChatGPT's responses to clinical pharmacy factual knowledge questions.
  • To compare ChatGPT's performance against that of human pharmacists.

Main Methods:

  • A dataset of 264 multiple-choice clinical pharmacy questions was used.
  • ChatGPT's answers were assessed for accuracy against established benchmarks.
  • Concordance, quality of substantiation (graded by pharmacists), and reproducibility were evaluated.
  • Results were compared to pharmacists' performance data from 2022.

Main Results:

  • ChatGPT achieved 79% accuracy, exceeding pharmacists' 66% accuracy.
  • Response concordance was high at 95%.
  • 73% of substantiations were rated as good or excellent, with high reproducibility (>92%).

Conclusions:

  • ChatGPT exhibits superior accuracy and reproducibility for factual clinical pharmacy questions compared to pharmacists.
  • The findings support ChatGPT's potential as a supplementary tool for clinical pharmacists.
  • Further technological advancements may enhance ChatGPT's utility in pharmacy practice.