Related Experiment Video
Updated: Jun 28, 2025

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
The role of tropospheric ozone in flagging COVID-19 pandemic transmission
1CNR-IMAA, Instutute of Methodologies for Environmental Analysis, 85050 Tito Scalo, PZ Italy.
Abstract:
COVID-19 pandemic outbreak, caused by the SARS-CoV-2 virus, affected millions of people worldwide causing hundreds of thousands of related fatalities. It is crucial to understand why the virus transmission seems to spread more easily in some regions than others. The residuals, with respect to the modeled COVID-19 per-day hospitalized patients in intensive care unit, are correlated to the meteorological and air-pollutant variables in four major metropolitan areas in Italy during a strict lockdown implemented by the Italian government, making the analysis independent from socio-economic factors. The results show that COVID-19 pandemic-related infections are slowed down by higher tropospheric ozone concentrations and eased by the atmospheric particulate. We quantitatively assessed that higher levels of tropospheric ozone, already proven effective against viruses and microbial contaminants, play a role in flagging COVID-19 pandemic transmission. Because the tropospheric ozone production is depending, among others, by air-quality and sunlight, this can explain why the virus is spreading in different ways.
Related Concept Videos
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Pneumonia II: Pathophysiology

