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Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
Published on: August 12, 2019
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Translational research: from basic research to regional biomedical entrepreneurship
Sang-Min Park1, Nicholas S Vonortas2,3
1Science, Technology and Innovation Support Team, Ministry of Science and ICT, Sejong Finance Center II, 194, Gareum-ro, Sejong-si, 30121 South Korea.
Small Business Economics
|April 16, 2024
Summary
Translational research modestly boosts biomedical patents and entrepreneurship, but not significantly through patents or clinical trials. This study explores regional impacts of research translation.
Area of Science:
- Biomedical Sciences
- Health Services Research
- Entrepreneurship Studies
Background:
- Translational research outputs are typically measured by academic publications.
- The link between translational research and biomedical entrepreneurship remains under-explored.
- Existing research has not fully integrated knowledge spillover and entrepreneurial ecosystem theories.
Purpose of the Study:
- To analyze the impact of translational research on knowledge production and biomedical entrepreneurship in U.S. regions.
- To investigate the relationship between translational research, biomedical patents, clinical trials, and entrepreneurship.
- To test an analytical model using the knowledge spillover theory and entrepreneurial ecosystem approach.
Main Methods:
- Constructed an analytical model integrating knowledge spillover theory and entrepreneurial ecosystem concepts.
- Utilized 10 years of panel data from 381 U.S. metropolitan statistical areas.
- Focused on data related to the National Institutes of Health (NIH) Clinical and Translational Science Awards (CTSA) program.
Main Results:
- The NIH Clinical and Translational Science Awards (CTSA) program showed a positive association with increased biomedical patents.
- CTSA also correlated with higher biomedical entrepreneurship, indicated by NIH Small Business Innovation Research (SBIR) grants.
- The influence of translational research on regional biomedical entrepreneurship was not substantially mediated by biomedical patents or clinical trials.
Conclusions:
- Translational research has a measurable but small effect on biomedical patents and entrepreneurship.
- Biomedical patents and clinical trials are not strong pathways for translational research to impact regional entrepreneurship.
- Further research is needed to understand the complex dynamics of translational research and its economic impact.
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