Related Experiment Video
Updated: Jun 28, 2025

Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic Minigenomes
Published on: September 27, 2014
Computational and stability analysis of Ebola virus epidemic model with piecewise hybrid fractional operator
Kottakkaran Sooppy Nisar1, Muhammad Farman2,3, Khadija Jamil4
1Department of Mathematics, College of Arts and Sciences, Prince Sattam bin Abdulaziz University, Wadi Aldawaser, Saudi Arabia.
Abstract:
In this manuscript, we developed a nonlinear fractional order Ebola virus with a novel piecewise hybrid technique to observe the dynamical transmission having eight compartments. The existence and uniqueness of a solution of piecewise derivative is treated for a system with Arzel'a-Ascoli and Schauder conditions. We investigate the effects of classical and modified fractional calculus operators, specifically the classical Caputo piecewise operator, on the behavior of the model. A model shows that a completely continuous operator is uniformly continuous, and bounded according to the equilibrium points. The reproductive number R0 is derived for the biological feasibility of the model with sensitivity analysis with different parameters impact on the model. Sensitivity analysis is an essential tool for comprehending how various model parameters affect the spread of illness. Through a methodical manipulation of important parameters and an assessment of their impact on Ro, we are able to learn more about the resiliency and susceptibility of the model. Local stability is established with next Matignon method and global stability is conducted with the Lyapunov function for a feasible solution of the proposed model. In the end, a numerical solution is derived with Newton's polynomial technique for a piecewise Caputo operator through simulations of the compartments at various fractional orders by using real data. Our findings highlight the importance of fractional operators in enhancing the accuracy of the model in capturing the intricate dynamics of the disease. This research contributes to a deeper understanding of Ebola virus dynamics and provides valuable insights for improving disease modeling and public health strategies.
More Related Videos
08:02Experimental Viral Infection in Adult Mosquitoes by Oral Feeding and Microinjection
Published on: July 28, 2022
08:10Production of High-Titer Infectious Influenza Pseudotyped Particles with Envelope Glycoproteins from Highly Pathogenic H5N1 and Avian H7N9 Viruses
Published on: January 15, 2020
Related Concept Videos
Steps in Outbreak Investigation
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
Multimachine Stability
In analyzing the system, the nodal equations represent the relationship between bus voltages, machine voltages, and machine currents. The nodal equation is given by:
Mechanistic Models: Compartment Models in Individual and Population Analysis
Routh-Hurwitz Criterion II
The first scenario occurs when a singular zero appears in the first column of the Routh table. This situation creates a division by zero issues. To resolve this, a small positive or negative number, denoted as epsilon (∈), is substituted for the zero. The stability analysis proceeds by assuming a sign for ∈. If ∈ is positive, any sign change in the first...
Pole and System Stability
Simple poles are unique roots of the denominator polynomial. Each simple pole corresponds to a distinct solution to the system's characteristic equation, typically resulting in exponential decay terms in the system's...