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Updated: Jun 28, 2025

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
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Drug-Induced Liver Injury in Pregnancy: The U.S. Drug-Induced Liver Injury Network Experience

Umair Masood1, Nicholas Venturini, Paola Nicoletti

  • 1Division of Liver Diseases and the Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York; Duke University School of Medicine and the Duke Clinical Research Institute, Durham, and Wake Forest University School of Medicine and Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina; National Institutes of Health, Bethesda, Maryland; Indiana University School of Medicine, Indianapolis, Indiana; and Albert Einstein Medical Center, Philadelphia, Pennsylvania.

Obstetrics and Gynecology
|April 16, 2024
PubMed
Summary

Drug-induced liver injury (DILI) during pregnancy is rare but more severe than in nonpregnant individuals. Key recommendations include deferring isoniazid and using alternative hypertension medications during pregnancy.

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