Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

2.8K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
2.8K
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

228
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
228
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

205
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
205
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
2.5K
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Predictive And Prognostic Markers
  11. Impact Of Latent Toxoplasmosis On Pneumonic And Non-pneumonic Covid-19 Patients With Estimation Of Relevant Oxidative Stress Biomarkers

Impact of latent toxoplasmosis on pneumonic and non-pneumonic COVID-19 patients with estimation of relevant oxidative stress biomarkers

Doaa A Hamdy1, Ragaey A Eid2, Heba Abdel-Tawab3

  • 1Department of Medical Parasitology, College of Medicine, Beni-Suef University, Beni-Suef, Egypt.

Folia Parasitologica
|April 17, 2024

Related Experiment Videos

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
14:48

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Published on: March 21, 2021

5.1K
Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors
09:33

Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors

Published on: February 7, 2018

7.5K
Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
08:17

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

10.9K

View abstract on PubMed

Summary
This summary is machine-generated.

Latent toxoplasmosis, an infection by *Toxoplasma gondii*, is strongly associated with an increased risk of COVID-19. This study found higher prevalence of *Toxoplasma gondii* antibodies in COVID-19 patients, indicating its potential as a risk indicator.

Area of Science:

  • Infectious Diseases
  • Immunology
  • Epidemiology

Background:

  • COVID-19 susceptibility varies across populations, with *Toxoplasma gondii* exposure proposed as a contributing factor.
  • Understanding co-infections and their impact on disease severity is crucial for public health.
  • Oxidative stress markers, C-reactive protein (CRP), and ferritin are implicated in inflammatory responses.

Purpose of the Study:

  • To investigate the association between latent toxoplasmosis and COVID-19.
  • To explore the correlation between latent toxoplasmosis, COVID-19, and markers of oxidative stress, CRP, and ferritin.

Main Methods:

  • A case-control study involving 91 confirmed COVID-19 patients (48 non-pneumonic, 43 pneumonic) and 45 healthy controls.
  • Measurement of IgG anti-Toxoplasma gondii antibodies.
Keywords:
C-reactive proteinSARS-CoV-2Toxoplasma gondiiantioxidants

Related Experiment Videos

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
14:48

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Published on: March 21, 2021

5.1K
Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors
09:33

Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors

Published on: February 7, 2018

7.5K
Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
08:17

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

10.9K
  • Assessment of oxidative stress markers (nitric oxide [NO], superoxide dismutase [SOD], reduced glutathione [GSH]), CRP, and serum ferritin.

    • Main Results:

    • Significantly higher prevalence of IgG anti-T. gondii antibodies in COVID-19 patients (54%) compared to controls (7%) (P < 0.001).
    • No significant correlation between COVID-19 severity and latent T. gondii infection.
    • Elevated NO and SOD, decreased GSH levels in COVID-19 patients; elevated CRP and ferritin in pneumonic COVID-19 patients with toxoplasmosis.

    Conclusions:

    • Latent toxoplasmosis is a strong indicator of increased risk for COVID-19.
    • The high prevalence suggests T. gondii infection may influence COVID-19 susceptibility.
    • This study highlights the role of oxidative stress indicators in COVID-19 and T. gondii co-infection.
    ferritin.