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Updated: Jun 28, 2025
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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
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Patient characteristics associated with acute kidney injury following coronary angiography
Jonathan Knott1, Michael Engheta2, Jeffery Michel2
1Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Proceedings (Baylor University. Medical Center)
|April 17, 2024
Summary
Peripheral artery disease and multivessel coronary artery disease significantly increase the risk of acute kidney injury (AKI) after coronary angiography. Patients with higher initial creatinine levels also face a greater chance of developing AKI.
Area of Science:
- Cardiology
- Nephrology
- Interventional Cardiology
Background:
- Coronary angiography is a common procedure, but it carries a risk of acute kidney injury (AKI).
- Identifying patient characteristics associated with AKI is crucial for risk stratification and prevention strategies.
Purpose of the Study:
- To identify patient characteristics associated with acute kidney injury (AKI) following coronary angiography with or without percutaneous coronary intervention.
Main Methods:
- Retrospective, single-center study of 350 patients from October 1, 2017, to September 30, 2018.
- AKI defined as a creatinine rise >0.3 mg/dL within 48 hours of coronary angiography.
- Multivariable regression analysis was used to identify independent predictors of AKI.
Main Results:
- The incidence of AKI was 8.8% (41 out of 350 patients).
- Patients with AKI had higher rates of hypertension, hyperlipidemia, diabetes mellitus, and heart failure.
- Peripheral artery disease (OR=12.4), multivessel coronary artery disease (OR=11.9), and initial creatinine >1.5 mg/dL (OR=4.4) were significantly associated with increased AKI risk.
Conclusions:
- Peripheral artery disease, multivessel coronary artery disease, and elevated baseline creatinine are key risk factors for AKI post-coronary angiography.
- These findings can aid in identifying high-risk patients and implementing preventive measures.
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