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Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience

Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience

Published on: November 15, 2024

CUREing biochemistry lab monotony.

Matthew J Satusky¹, Hunter Wilkins¹, Bryant Hutson²

¹Department of Chemistry, University of North Carolina, Chapel Hill, NC 27599, USA.

Journal of Chemical Education

|April 17, 2024

Summary

This summary is machine-generated.

This biochemistry course-based undergraduate research experience (CURE) offers realistic graduate-level training. Students gained confidence in experimental techniques and project ownership through multi-semester research on a DNA helicase.

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Published on: December 6, 2010

Area of Science:

Biochemistry
Molecular Biology
Undergraduate Education

Background:

Undergraduate research experience is crucial for postgraduate success.
Course-Based Undergraduate Research Experiences (CUREs) offer inclusive research opportunities, moving beyond traditional "cookbook" labs.
This study focuses on an upper-level biochemistry CURE simulating graduate-level research.

Purpose of the Study:

To describe an upper-level biochemistry CURE focused on studying a suspected DNA helicase.
To assess the impact of the CURE on student confidence, perceptions, and project ownership.
To evaluate the effectiveness of incorporating lab meeting-style recitations and poster presentations.

Main Methods:

An upper-level biochemistry CURE spanning multiple semesters was implemented.
Student cohorts built upon the research of previous semesters.
Pre- and post-course surveys assessed student confidence, perceptions, and project ownership.

Main Results:

Incorporating lab meeting-style recitations and poster presentations increased project ownership.
Overcoming experimental troubleshooting presented a significant challenge for students.
Confidence in most experimental techniques significantly increased post-course.

Conclusions:

The biochemistry CURE provides students with a realistic introduction to graduate-level research.
The multi-semester, cohort-based approach fosters a sense of project ownership.
The CURE effectively enhances undergraduate students' confidence and skills in biochemical research techniques.