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A Case Report on Fever of Unknown Origin in a 10-Year-Old: Tubercular Liver Abscess
Sumita Biswas1, Md Wahiduzzaman Mazumder2, Uma Gupta3
1Pediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, BGD.
Insights
Pediatric liver tuberculosis is rare but treatable. Early diagnosis via liver biopsy and targeted therapy can resolve symptoms in children with tubercular liver abscesses.
Area of Science:
- Pediatric Infectious Diseases
- Hepatology
- Microbiology
Background:
- Liver tuberculosis is an uncommon presentation in pediatric patients.
- Solitary tubercular liver abscesses require multidisciplinary management.
Observation:
- A previously healthy 10-year-old male presented with fever of unknown origin.
- Diagnostic workup revealed a tubercular liver abscess.
Findings:
- Liver biopsy with immunohistochemistry confirmed the presence of tubercular pathogens.
- Targeted anti-tuberculosis therapy led to complete resolution of fever.
Implications:
- Highlights the importance of considering liver tuberculosis in febrile children.
- Emphasizes the need for early diagnosis and collaborative treatment approaches.
- Suggests immunohistochemistry as a valuable diagnostic tool for hepatic tuberculosis.
Abstract:
The liver, which presents as a focal point for tuberculosis in pediatric cases, is rarely encountered, and reported instances are scarce. This atypical manifestation underscores the management of tuberculosis affecting this particular organ in the context of pediatric patients. The treatment of solitary tubercular liver abscesses in children necessitates a collaborative approach, engaging pediatricians, infectious disease specialists, and interventional radiologists. It also needs awareness among physicians to explore and treat early and to complete further assessments for a better outcome. In our instance, investigating the cause of fever led us to diagnose a tubercular liver abscess in a previously healthy 10-year-old male. The substantiation of this diagnosis was accomplished through a meticulous liver biopsy, wherein immunohistochemistry was employed to detect tubercular pathogens. Following the confirmation of the diagnosis, the initiation of a targeted therapeutic regimen resulted in the subsequent resolution of the fever.
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