Turn-on fluorescent aptasensing for the determination of serotonin via target-induced knot displacement at corona
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Updated: Jun 28, 2025

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A Time-Efficient Fluorescence Spectroscopy-Based Assay for Evaluating Actin Polymerization Status in Rodent and Human Brain Tissues
Published on: June 3, 2021
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M A Hagir Omer1, Danyang Zhang1, Wenshuai Zhou1
1Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710119, P. R. China. xlyang@snnu.edu.cn.
Abstract:
A turn-on fluorescence aptasensing approach for the highly sensitive and selective determination of 5-HT was proposed via target-induced knot displacement. 5-HT can be determined in a range from 0.5 nM to 100 nM with a limit of detection as low as 0.1 nM and a low dissociation constant of 2.3 nM.

