Tabletized Nanomedicine: From the Current Scenario to Developing Future Medicine

Area of Science:

• * Pharmaceutical Sciences and Nanotechnology

Background:

• * Conventional therapies face limitations, driving innovation in nanotechnology-based medical formulations (nanomedicine). * Nanomedicine involves embedding therapeutic agents within biodegradable or biocompatible nanomaterials. * Tabletized nanomedicine, an oral drug delivery system, is an emerging area of research.

Purpose of the Study:

• * To document perspectives and opportunities for developing nanoformulations into tabletized nanomedicine. * To explore the integration of nanomedicine within tablet formulations for controlled release. * To review current trends and applications in tabletized nanomedicine, including nanotheranostics.

Main Methods:

• * Literature review of existing research on nanomedicine and tablet formulations. * Analysis of the interplay between nanoformulations and the gastrointestinal tract environment. * Exploration of emerging nanomedicine technologies for oral delivery.

Main Results:

• * Nanoformulations integrated into tablets can facilitate controlled release of drugs and biomolecules. * This controlled release enhances therapeutic responses compared to conventional methods. * The gastrointestinal tract's milieu significantly influences the performance of tabletized nanomedicine.

Conclusions:

• * Tabletized nanomedicine presents significant opportunities for advanced oral drug delivery. * Integrating nanomedicine into tablets enables precise control over therapeutic agent release. * Emerging trends like nanotheranostics and specific agent delivery (bacteriophage, probiotics, oligonucleotides) show promise.