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Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

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Related Experiment Video

Updated: Jun 28, 2025

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography

Published on: January 17, 2025

CT Scan Data Analysis in Malformations of Cortical Development.

Marcello Scala^1,2, Mariasavina Severino^1,3

¹Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.

Methods in Molecular Biology (Clifton, N.J.)

|April 17, 2024

Summary

This summary is machine-generated.

Computed tomography (CT) has limited use for diagnosing malformations of cortical development (MCDs), but it can detect calcifications and associated skeletal anomalies, aiding in differential diagnosis when MRI is unavailable.

Keywords:

Brain malformations CT scan Computed tomography Cortical development Malformations of cortical development Radiations

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Area of Science:

Neuroscience
Radiology
Medical Imaging

Background:

Malformations of cortical development (MCDs) encompass a range of disorders arising from aberrant neuronal processes during fetal brain development.
Accurate diagnosis of MCDs is crucial for appropriate management and genetic counseling.

Conclusions:

CT is a valuable adjunct in MCD evaluation, especially for detecting calcifications and associated skeletal anomalies, and serves as an alternative when MRI is contraindicated or unavailable.
The review outlines CT scan techniques and data analysis for optimizing its use in the diagnostic workup of MCDs.