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Updated: Jun 28, 2025

A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model
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Characterization of relapse-supportive monocytic cells in acute myeloid leukemia
1Department of Biological Chemistry, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA.
Abstract:
The precise identities of bone marrow resident cells contributing to AML relapse are not fully known. Hollands et al. report early evidence to support the existence of an aberrant monocytic cell population that appears to promote LSC expansion after cytarabine treatment.
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