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Development of the Blood Stasis Questionnaire for Gynecological Diseases: An Analytical Cross-Sectional Study
Byoung-Kab Kang1, Soobin Jang2, Mi Mi Ko1
1KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
Insights
The Blood Stasis Questionnaire for Gynecological Disease (BSQ-GD) effectively identifies blood stasis in women. This validated tool offers high diagnostic accuracy for gynecological conditions.
Area of Science:
- Integrative Medicine
- Gynecology
- Medical Diagnostics
Background:
- Blood stasis, characterized by slowed or stagnant blood flow, is linked to various metabolic, musculoskeletal, and gynecological diseases.
- Existing questionnaires (BSQ-I and BSQ-II) provided a foundation for developing a specialized tool for gynecological applications.
Purpose of the Study:
- To develop and validate the Blood Stasis Questionnaire for Gynecological Disease (BSQ-GD).
- To assess the reliability and diagnostic accuracy of the BSQ-GD in identifying blood stasis in women with gynecological conditions.
Main Methods:
- The BSQ-GD was developed using clinical indicators from BSQ-I and BSQ-II.
- 103 women (25-65 years) with gynecological diseases were enrolled in a cross-sectional study.
- Reliability was assessed using Cronbach's alpha; validity was confirmed through correlation and discriminant analyses. Logistic regression determined prediction accuracy and cut-off values.
Main Results:
- The BSQ-GD demonstrated satisfactory internal consistency (Cronbach's α = 0.71) and validity.
- Significant differences in scores were observed between blood stasis (22.30 ± 3.34) and non-blood stasis (14.93 ± 3.49) groups.
- The optimal cut-off score was 19, with high diagnostic accuracy (AUC ~96%), sensitivity (80.95%), and specificity (92.50%).
Conclusions:
- The BSQ-GD is a suitable instrument for estimating blood stasis in patients with gynecological diseases.
- The questionnaire exhibits high diagnostic sensitivity when utilizing the established cut-off value.
Objectives:
Blood stasis is the slowing or stagnation of blood and can cause metabolic, musculoskeletal, and gynecological diseases. This study developed the Blood Stasis Questionnaire for gynecological disease (BSQ-GD) by extracting clinical indicators related to gynecological diseases using the Blood Stasis Questionnaires I and II (BSQ-I and II, respectively) and analyzed the clinical data of a cross-sectional study.
Patients And Methods:
In total, 103 women aged between 25 and 65 years who met gynecological disease criteria were enrolled in this study. Blood stasis scores (BSS) were evaluated using the BSQ-II and categorized into BSS and non-BSS groups. To assess the reliability of BSQ-GD, the internal consistency coefficient was employed using Cronbach's α. Furthermore, correlation analyses were conducted for the clinical symptoms related to gynecological diseases, and the discriminant validity was confirmed by comparing the two groups. The prediction accuracy was determined using logistic regression and the cut-off value of the BSQ-GD was established via the sensitivity and specificity calculations.
Results:
The BSQ-GD showed satisfactory internal consistency (Cronbach's α coefficient = 0.71) and validity, with significant differences in mean scores between blood stasis (22.30 ± 3.34) and non-blood stasis (14.93 ± 3.49) groups. The cut-off value of the BSQ-GD score was 19 points when the Youden index (73.45) and the concordance probability (0.75) were at their maximum. The area under the receiver operating characteristic curve was approximately 96%, and the sensitivity and specificity of the diagnostic accuracy according to the cut-off value are 80.95% and 92.50%, respectively.
Conclusion:
The BSQ-GD can be an appropriate instrument to estimate blood stasis in patients with gynecological diseases; its diagnostic sensitivity according to the cut-off value is high.
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