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Shared functions of Fe-S cluster assembly and Moco biosynthesis

Muhammad Abrar Hasnat1, Silke Leimkühler1

  • 1University of Potsdam, Institute of Biochemistry and Biology, Department of Molecular Enzymology, Karl-Liebknecht Str. 24-25, 14476 Potsdam-Golm, Germany.

Biochimica Et Biophysica Acta. Molecular Cell Research
|April 17, 2024
PubMed
Summary

Molybdenum cofactor (Moco) biosynthesis relies on iron-sulfur (Fe-S) clusters. This review details how Fe-S cluster availability, gene regulation by FNR, and sulfur delivery impact Moco production and active molybdoenzymes.

Keywords:
FNRFeS clustersGene regulationIronMolybdenum cofactor

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