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Tuberculosis in pregnancy and assisted reproductive technology
Wenli Cao1, Xiayan Fu1, Haiyang Li1
1Reproductive Medicine Center, Zhoushan Maternal and Child Health Care Hospital, Zhoushan, Zhejiang, China.
Drug Discoveries & Therapeutics
|April 17, 2024
Summary
Tuberculosis impacts women's reproductive health, potentially causing infertility and requiring assisted reproduction. Pregnant women with latent tuberculosis need monitoring, while active tuberculosis demands early, multidisciplinary treatment to protect mother and child.
Area of Science:
- Reproductive Medicine
- Infectious Diseases
- Public Health
Background:
- Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis.
- TB significantly affects women's reproductive health, leading to infertility.
- Latent TB in pregnancy poses risks, potentially progressing to active disease.
Purpose of the Study:
- To review the impact of tuberculosis on female reproductive health.
- To discuss management strategies for latent and active tuberculosis during pregnancy.
- To highlight the importance of early diagnosis and multidisciplinary treatment.
Main Methods:
- Literature review of tuberculosis and reproductive health studies.
- Analysis of clinical manifestations and outcomes of TB in pregnant women.
- Synthesis of current guidelines for TB management in pregnancy.
Main Results:
- Tuberculosis can cause anatomical abnormalities, implantation issues, and ovulatory dysfunction, contributing to female infertility.
- Latent TB during pregnancy is often asymptomatic but can progress, risking adverse outcomes.
- Early diagnosis and treatment of active TB in pregnancy are crucial for reducing maternal and neonatal morbidity and mortality.
Conclusions:
- Tuberculosis is a significant threat to women's reproductive health and fertility.
- Management of latent TB in pregnancy requires careful monitoring, especially for high-risk individuals.
- Prompt, collaborative treatment of active TB in pregnant women is essential for favorable outcomes.
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