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Updated: Jun 28, 2025

Using Real-Time Cell Metabolic Flux Analyzer to Monitor Osteoblast Bioenergetics
Published on: March 1, 2022
New insights into the vitamin D/PTH axis in endocrine-driven metabolic bone diseases
Luigi di Filippo1, John P Bilezikian2, Ernesto Canalis3
1Institute of Endocrine and Metabolic Sciences, San Raffaele Vita Salute University and IRCCS San Raffaele Hospital, Milan, Italy.
Background:
Endocrine regulation of bone metabolisms is the focus of the "Skeletal Endocrinology" series of meetings.
Aims:
To report on the outcome of the discussion on the role of vitamin D/PTH axis in endocrine osteopathies held during the 10th Skeletal Endocrinology Meeting which took place in Stresa (Italy) in March 2023.
Outcomes:
Vitamin D/PTH axis has relevant influence on several outcomes in the general population and in patients affected by endocrinopathies such as hypoparathyroidism and secreting pituitary adenomas.
Conclusions:
Assessing the status of the vitamin D/PTH axis and using vitamin D and PTH as therapeutic agents is mandatory in several endocrine-related bone metabolic conditions.
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