Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anatomy of the Intestines01:23

Anatomy of the Intestines

71.8K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
71.8K
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

272
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
272
Bacterial Flora of the Large Intestine01:29

Bacterial Flora of the Large Intestine

435
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
435
Physiology of Enteric Nervous System and Gut Health01:05

Physiology of Enteric Nervous System and Gut Health

261
The gastrointestinal tract, responsible for the digestion and absorption of nutrients, is safeguarded by the intestinal barrier, which consists of secretory, physical, and immune components. At the forefront is the secretory barrier, composed of essential elements such as mucus, gut microbiota, and defense proteins. They collaborate to break down food particles, facilitate nutrient absorption, and maintain optimal gut health. These secretory components ensure the smooth functioning of the...
261
Neural Regulation01:37

Neural Regulation

39.4K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The rise of Mendelian randomization for exploring disease causality: A bibliometric analysis based on CiteSpace.

Medicine·2025
Same author

Stable multifunctional aluminum phosphides at high pressures.

Physical chemistry chemical physics : PCCP·2023
Same author

A novel visceral adiposity index predicts bone loss in female early rheumatoid arthritis patients detected by HR-pQCT.

Scientific reports·2023
Same author

A copper-metal organic framework enhances the photothermal and chemodynamic properties of polydopamine for melanoma therapy.

Acta biomaterialia·2023
Same author

Triplex-forming oligonucleotides as an anti-gene technique for cancer therapy.

Frontiers in pharmacology·2023
Same author

A SiO<sub>2</sub> layer on PEO-treated Mg for enhanced corrosion resistance and bone regeneration.

Frontiers in bioengineering and biotechnology·2023
Same journal

Hypogonadotrophic hypogonadism in GBA2 associated spastic paraplegia type 46 (SPG46): a phenotypic expansion.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Vibrotactile stimulation induces changes in basal ganglia output, cervical muscle activity, and head posture in a patient with cervical dystonia.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Evaluating LLM diagnostic reasoning: a new frontier for clinical AI assessment.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Asymmetrical muscular disorder with normal creatine kinase (CK) and electromyography (EMG): the challenging diagnosis of muscular polyarteritis nodosa (MPAN), case report and literature review.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Neuropsychological assessment in adult epilepsy: rationale, test selection, and clinical integration across non-surgical care in Italian patients.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same journal

Early implementation of transradial mechanical thrombectomy in a primary stroke center: a sequential cohort propensity score-matched study.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
See all related articles

Related Experiment Video

Updated: Jun 28, 2025

Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice
07:49

Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice

Published on: June 2, 2022

3.2K

Research progress on intestinal microbiota regulating cognitive function through the gut-brain axis.

Kaijie Lin1, Feng Peng1,2, Kunyang He1

  • 1School of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan, China.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|April 17, 2024
PubMed
Summary
This summary is machine-generated.

The gut microbiome influences brain function and cognition via the gut-brain axis. Perioperative gut dysbiosis may cause neurocognitive dysfunction, necessitating new prevention strategies.

Keywords:
Cognitive functionIntestinal microbiotaPerioperative neurocognitive dysfunctionPost-anesthesia/surgeryThe gut-brain axis

More Related Videos

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
07:15

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

9.6K
A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis
09:18

A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis

Published on: July 28, 2023

2.6K

Related Experiment Videos

Last Updated: Jun 28, 2025

Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice
07:49

Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice

Published on: June 2, 2022

3.2K
An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
07:15

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

9.6K
A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis
09:18

A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis

Published on: July 28, 2023

2.6K

Area of Science:

  • Microbiology
  • Neuroscience
  • Gastroenterology

Background:

  • The intestinal microbiota is crucial for health and disease management.
  • The gut-brain axis links gut microbes to central nervous system cognitive regulation.
  • Intestinal microbiota impacts cognition through neural and circulatory pathways.

Purpose of the Study:

  • To review literature on intestinal microbiota's influence on brain and cognitive functions.
  • To explore the role of the nervous and circulatory systems in this interaction.
  • To summarize findings on perioperative gut dysbiosis and neurocognitive dysfunction.

Main Methods:

  • Literature review of existing research.
  • Analysis of studies investigating the gut-brain axis.
  • Synthesis of findings on perioperative intestinal dysbiosis.

Main Results:

  • Intestinal microbiota significantly impacts cognitive functions.
  • Perioperative intestinal dysbiosis is linked to neurocognitive dysfunction.
  • The gut-brain axis is a key pathway for microbial influence on cognition.

Conclusions:

  • Intestinal microbiota plays a critical role in cognitive function.
  • Perioperative interventions targeting the gut microbiome may prevent neurocognitive dysfunction.
  • Further research is needed to develop effective prevention and treatment strategies.