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Updated: Jun 28, 2025

Formulation of Diblock Polymeric Nanoparticles through Nanoprecipitation Technique
Published on: September 20, 2011
Effect of polymer concentration on the morphology of the PHPMAA-g-PLA graft copolymer nanoparticles produced by
Svetlana Lukáš Petrova1, Ewa Pavlova1, Václav Pokorný1
1Institute of Macromolecular Chemistry v.v.i., Academy of Sciences of the Czech Republic Heyrovsky Sq. 2 162 06 Prague 6 Czech Republic petrova@imc.cas.cz.
Abstract:
Successful generation of micelles, vesicles, and/or worms with controllable sizes was achieved through the self-assembly process of the poly[N-(2-hydroxypropyl)]methacrylamide-g-polylactide (PHPMAA-g-PLA) graft copolymer within a microfluidic channel. A product diagram was created to illustrate various morphologies associated with different polymer concentrations, all while maintaining a constant flow velocity ratio between water and the polymer solution.

