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HIV and SARS-Cov-2 Co-Infection: A Local Perspective
Heval Can Bilek1, Aydın Deveci1
1Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayıs University School of Medicine, Samsun, Turkey.
Infectious Diseases & Clinical Microbiology
|April 18, 2024
Summary
Human immunodeficiency virus (HIV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) co-infection did not worsen COVID-19 outcomes. HIV patients on antiretroviral therapy (ART) showed mild COVID-19, with no increased mortality.
Area of Science:
- Infectious Diseases
- Virology
- Immunology
Background:
- The COVID-19 pandemic caused by SARS-CoV-2 has impacted global health.
- Co-infection with HIV in SARS-CoV-2 positive patients raises concerns about clinical outcomes.
- Understanding the interplay between HIV and SARS-CoV-2 is crucial for patient management.
Purpose of the Study:
- To evaluate the clinical course of patients co-infected with HIV and SARS-CoV-2.
- To assess the impact of HIV on COVID-19 severity and mortality.
- To provide a local perspective on managing co-infected patients.
Main Methods:
- Retrospective analysis of HIV and SARS-CoV-2 co-infected patients.
- Data collected from March 2020 to June 2021 at a tertiary hospital in Turkey.
- Inclusion of 30 co-infected patients, analyzing demographics, HIV status, ART, and COVID-19 outcomes.
Main Results:
- The majority of co-infected patients (27/30) experienced a mild course of COVID-19.
- Three patients were hospitalized, two of whom were ART-naïve males and unfortunately died.
- All patients known to be HIV-positive were on ART and virologically suppressed, with no increased COVID-19 severity.
Conclusions:
- HIV infection alone did not increase the severity of COVID-19.
- HIV status and ART adherence did not significantly increase mortality in COVID-19 patients.
- ART-suppressed HIV patients exhibit similar COVID-19 clinical courses to the general population.
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