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Updated: Jun 28, 2025

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Published on: September 28, 2022
The Endometrial Stem/Progenitor Cells and Their Niches
Baolan Sun1,2, Xi Cheng3, Qiang Wu4
1Department of Clinical Laboratory, Affiliated Hospital of Nantong University, Nantong, China. lanbao0218@163.com.
Abstract:
Endometrial stem/progenitor cells are a type of stem cells with the ability to self-renew and differentiate into multiple cell types. They exist in the endometrium and form niches with their neighbor cells and extracellular matrix. The interaction between endometrial stem/progenitor cells and niches plays an important role in maintaining, repairing, and regenerating the endometrial structure and function. This review will discuss the characteristics and functions of endometrial stem/progenitor cells and their niches, the mechanisms of their interaction, and their roles in endometrial regeneration and diseases. Finally, the prospects for their applications will also be explored.

