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Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection
Published on: November 7, 2018
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Prevalence of hepatitis B virus infection and its associated factors among students in N'Djamena, Chad
Nalda Debsikréo1,2, Birwé Léon Mankréo1, Azoukalné Moukénet1,3
1Cheikh Anta Diop University, Dakar, Senegal.
Plos One
|April 18, 2024
Summary
Hepatitis B virus (HBV) infection affects 14.87% of N'djamena university students. Key risk factors include an HBsAg-positive mother, medical procedures, and living with family, highlighting the need for targeted prevention strategies.
Area of Science:
- Hepatology
- Public Health
- Epidemiology
Background:
- Hepatitis B virus (HBV) infection poses a significant global public health challenge.
- Chad exhibits a notable HBV prevalence of 12.4% across all age demographics.
Purpose of the Study:
- To ascertain the prevalence of HBV infection among university students in N'Djamena, Chad.
- To identify factors associated with HBV infection within this student population.
Main Methods:
- A cross-sectional survey was conducted among 457 students from July 3-23, 2021.
- Hepatitis B surface antigen (HBsAg) was tested using rapid kits and confirmed with automated analyzers.
- Descriptive and logistic regression analyses were employed to identify significant associations.
Main Results:
- The prevalence of HBV infection among N'Djamena students was found to be 14.87%.
- Significant risk factors included having an HBsAg-positive mother (AOR: 2.11), history of transcutaneous medical procedures (AOR: 2.97), and living with family (AOR: 4.63).
- Age 26 years or older was identified as a protective factor (AOR: 0.41).
Conclusions:
- The study reveals a high HBV prevalence of 14.87% in N'Djamena's university student population.
- Recommendations include enhanced student awareness campaigns, mandatory hepatitis B vaccination prior to schooling, widespread screening, and reduced vaccination costs.
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