Related Experiment Video
Updated: Jun 28, 2025
06:44
Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging
Published on: June 7, 2020
7.3K
Metastases Affecting Cranial Nervous Structures in Male Breast Cancer: Two Case Reports
Andrea Valera-Barrero1, Jorge Madera-Fernández1,2, Vicente González-Quintanilla1,2
1Neurology Service, Marqués de Valdecilla University Hospital, Santander, Spain.
Oncology Research and Treatment
|April 18, 2024
Summary
Male breast cancer rarely spreads to the head, but when it does, it impacts middle-aged men. Early detection and understanding this rare metastatic pattern are crucial for better outcomes.
Area of Science:
- Oncology
- Neurology
- Pathology
Background:
- Male breast cancer is rare, with diagnosis often delayed, leading to higher rates of metastatic disease.
- Early detection tools for male breast cancer are lacking, contributing to advanced stage at diagnosis.
- Characteristics of head metastases in male breast cancer are not well-defined.
Observation:
- Presents two cases of male breast cancer with metastases involving cranial nervous structures.
- Both patients were middle-aged with ductal-type, HER-2 negative, and androgen receptor positive primary tumors.
- Imaging and histologic data were provided for both cases.
Findings:
- Central nervous system involvement in male breast cancer, while uncommon, can occur.
- Metastases affected cranial nervous structures in the presented cases.
- The primary tumors were characterized as ductal-type, HER-2 negative, and androgen receptor positive.
Implications:
- Clinicians should consider male breast cancer in middle-aged men presenting with focal neurological symptoms.
- Further research and case studies are needed to elucidate the biology of male breast cancer with cranial metastases.
- Improved understanding will aid in establishing adequate diagnostic and treatment strategies for this rare presentation.
Related Concept Videos
01:19Cranial Nerves: Overview and Anatomy
1.7K
The cranial nerves are an important part of the complex network of nerves in the human body. These nerves emerge directly from the brain and are responsible for transmitting essential information between the brain and various parts of the head and neck. There are 12 pairs of cranial nerves, systematically numbered using Roman numerals from I to XII, beginning from the anterior and moving to the posterior of the brain. Each cranial nerve is uniquely identified by names that reflect its function...
1.7K
01:22Cranial Nerves: Types Part II
2.4K
Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves. While the first six innervate the head and neck, the latter six nerves innervate the head and neck, as well as organs and tissues in the thoracic and abdominal cavities. They facilitate communication, expression, and autonomic control within the human body.
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
2.4K
01:14Cranial Nerves: Types Part I
2.6K
Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves, with the first six being essential in sensory perception, motor control, and autonomic functions related to the head and neck.
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
2.6K
01:03Olfactory Receptors: Location and Structure
9.2K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
9.2K