Queering genomics: How cisnormativity undermines genomic science

Area of Science:

• Genomic science, queer theory, and social justice.

Background:

• Genomics has historically been misused to justify social inequalities and discrimination.
• Scientific understanding of human biology and disease has advanced, yet genomics has also supported harmful arguments about inherent group differences.

Purpose of the Study:

• To explore how genomics reinforces scientifically unsound ideas about sex and gender.
• To examine the impact of flawed genomic research practices on transgender and intersex populations.
• To apply queer theory to illuminate issues within genomic science.

Main Methods:

• Analysis of current practices in genomic research and clinical applications.
• Application of queer theory to critique existing methodologies and their social implications.
• Review of how genomic data collection and interpretation can lead to stigmatization and exclusion.

Main Results:

• Imprecise genomic data practices contribute to the stigmatization of individuals with non-binary sex and/or gender identities.
• Current genomic research can generate inaccurate conclusions, supporting discriminatory public policies.
• Transgender and intersex individuals face barriers to quality healthcare and research participation due to flawed genomic science.

Conclusions:

• Genomic science must adopt more inclusive and accurate practices to avoid perpetuating harm.
• Queer theory offers valuable insights for improving genomic research and clinical applications.
• Researchers and clinicians should leverage genomics to promote health equity and understanding across diverse sex and gender spectra.