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Updated: Jun 28, 2025

Isolation of Neonatal Extrahepatic Cholangiocytes
Published on: June 5, 2014
Atypical Intrahepatic Cholestasis of Pregnancy: A Red Herring
Blake H Bentley1, Alexa E Cecil1, William C Lippert1
1Department of Internal Medicine. Wake Forest University School of Medicine, Winston-Salem, NC.
Abstract:
Intrahepatic cholestasis of pregnancy is an intrahepatic etiology of acute cholestasis commonly defined by pruritus and increased bile acids, liver transaminases, and, occasionally, bilirubin. Azathioprine is an immunosuppressive agent associated with various forms of hepatoxicity, ranging from transient rises in serum aminotransferase levels, acute cholestatic injury, and chronic hepatic injury. In this report, we present a 20-year-old pregnant woman who presented with cholestatic liver injury due to intrahepatic cholestasis of pregnancy with a clinical picture complicated by increased levels of azathioprine metabolites.
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