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Updated: May 5, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Periprocedural Bridging Therapy in Patients With Mechanical Heart Valves
Nivedha Balaji1, Oluwafemi Olukayode1, Fardeen Faiz2
1Internal Medicine, Northeast Georgia Medical Center Gainesville, Gainesville, USA.
Abstract:
Mechanical heart valves (MHVs) are thrombogenic and require lifelong anticoagulation with vitamin K antagonists (VKAs) such as warfarin. Periprocedural bridging with unfractionated heparin (UFH) and low-molecular-weight heparin (LMWH) aims to reduce the risk of thromboembolic events in patients. Currently, there are no definitive class I recommendations for anticoagulation management in patients with MHVs. In this report, we present the case of a 77-year-old female who was perioperatively bridged with enoxaparin and subsequently developed an acute thrombus.
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