Paper-based sensors: affordable, versatile, and emerging analyte detection platforms

Area of Science:

• Analytical Chemistry
• Materials Science

Background:

• Paper-based analytical devices (PADs) are emerging as a cost-effective and accessible technology for analyte detection.
• Their unique properties enable versatile applications across various scientific fields.

Purpose of the Study:

• To highlight the key attributes of paper-based sensors for analyte detection.
• To explore diverse fabrication methods and potential advancements in PAD technology.

Main Methods:

• Review of existing literature on paper-based sensor technology.
• Analysis of fabrication techniques including inkjet printing, wax printing, screen printing, dip coating, and photolithography.
• Exploration of incorporating nanomaterials and biorecognition elements.

Main Results:

• PADs offer a versatile, affordable, and accessible platform for detecting a wide range of analytes (chemical species, biomolecules, pathogens).
• User-friendly operation and minimal infrastructure requirements make PADs suitable for point-of-care diagnostics, environmental monitoring, and food safety.
• Various fabrication methods allow for customizable designs tailored to specific applications.

Conclusions:

• Paper-based sensors represent a transformative technology in analytical chemistry.
• Future advancements incorporating nanomaterials and biorecognition elements promise enhanced sensitivity and sophistication for PADs.