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Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

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Paper-based sensors: affordable, versatile, and emerging analyte detection platforms.

Sumit Malik1, Joginder Singh1, Kajal Saini1

  • 1Department of Chemistry, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, 133203, Haryana, India. joginderchem@mmumullana.org.

Analytical Methods : Advancing Methods and Applications
|April 19, 2024
PubMed
Summary

Paper-based analytical devices (PADs) offer an affordable and versatile platform for detecting various analytes. This review explores their attributes, fabrication methods, and potential for advanced applications in diagnostics and monitoring.

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Area of Science:

  • Analytical Chemistry
  • Materials Science

Background:

  • Paper-based analytical devices (PADs) are emerging as a cost-effective and accessible technology for analyte detection.
  • Their unique properties enable versatile applications across various scientific fields.

Purpose of the Study:

  • To highlight the key attributes of paper-based sensors for analyte detection.
  • To explore diverse fabrication methods and potential advancements in PAD technology.

Main Methods:

  • Review of existing literature on paper-based sensor technology.
  • Analysis of fabrication techniques including inkjet printing, wax printing, screen printing, dip coating, and photolithography.
  • Exploration of incorporating nanomaterials and biorecognition elements.

Main Results:

  • PADs offer a versatile, affordable, and accessible platform for detecting a wide range of analytes (chemical species, biomolecules, pathogens).
  • User-friendly operation and minimal infrastructure requirements make PADs suitable for point-of-care diagnostics, environmental monitoring, and food safety.
  • Various fabrication methods allow for customizable designs tailored to specific applications.

Conclusions:

  • Paper-based sensors represent a transformative technology in analytical chemistry.
  • Future advancements incorporating nanomaterials and biorecognition elements promise enhanced sensitivity and sophistication for PADs.