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Adalimumab as treatment for neurosarcoidosis: A case series
Jeffrey Shen1, Megumi Sugita2, Andrea Linares-Lopez2
1Duke University Hospital, Department of Rheumatology, United States.
Abstract:
Sarcoidosis is a disease characterized by non-caseating granulomas that can involve the central nervous system as neurosarcoidosis. This challenging disease is currently managed with high dose steroids, and sometimes the addition of infliximab. Other TNA-alpha inhibitors have not been studied as rigorously. We discovered ten neurosarcoidosis patients who were on an alternative TNA-alpha inhibitor, adalimumab. Eight patients had a positive response clinically and radiographically to adalimumab.
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