Preoperative aspirin and anticoagulants do not affect partial nephrectomy bleeding.

Area of Science:

• Nephrology
• Urology
• Cardiology

Background:

• Mixed conclusions exist regarding antiplatelet/anticoagulant agents and partial nephrectomy complications.
• Hemorrhagic complications are a concern in partial nephrectomy patients on these medications.

Purpose of the Study:

• To investigate the impact of preoperative anticoagulation on hemorrhagic complication risk after partial nephrectomy.
• To determine if aspirin use affects postoperative outcomes in partial nephrectomy.

Main Methods:

• Retrospective chart review of partial nephrectomies (2017-2022).
• Data collected on anticoagulation type, dose, and cessation timing.
• Bivariate analyses (t-tests, ANOVA) and Chi-Square tests used for statistical analysis.

Main Results:

• No significant difference in bleeding complications between patients on anticoagulation and those not.
• Aspirin use or continuation did not correlate with increased intraoperative or postoperative complications.
• Adjusted analyses confirmed no difference in blood loss or complications based on anticoagulation/aspirin status.

Conclusions:

• Prior anticoagulation or aspirin use does not solely increase partial nephrectomy complication rates with proper preoperative cessation.
• Patients on anticoagulation are not at higher risk for bleeding complications during partial nephrectomy.