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Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling
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Clinical characteristics of neonatal and infant osteomyelitis and septic arthritis: a multicenter retrospective study

Keming Sun1, Chunxu Zhang1, Ziwen Mao2

  • 1Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Department of Orthopaedic Surgery, Zhengzhou, Henan, China.

Jornal De Pediatria
|April 20, 2024
PubMed

Insights

Neonates and infants exhibit distinct clinical features and pathogens in osteoarticular infections. Early recognition of these differences is crucial for timely diagnosis and effective treatment of bone infections in young children.

Area of Science:

  • Pediatric Infectious Diseases
  • Neonatal and Infant Health
  • Musculoskeletal Infections

Background:

  • Osteomyelitis and septic arthritis in neonates and infants often present with nonspecific signs, leading to delayed diagnosis.
  • Early bone infections in this age group can be subtle and easily missed by clinicians.

Purpose of the Study:

  • To analyze the clinical characteristics of osteoarticular infections in neonates and infants.
  • To improve the understanding and diagnostic capabilities for these bone infections in young children.

Main Methods:

  • Retrospective multicenter study of neonates (0-28 days) and infants (1-12 months) with osteoarticular infections.
  • Data collected included clinical features, complications, laboratory results, and causative microorganisms.
  • Statistical analysis compared differences between neonates and infants, and regional variations.

Main Results:

  • Neonates showed less fever, more localized swelling, and higher rates of humerus infections compared to infants.
  • Escherichia coli and Klebsiella pneumoniae were more prevalent in neonates, while Staphylococcus aureus was more common in infants.
  • Neonates were more prone to developing septic arthritis.

Conclusions:

  • Significant clinical and microbiological differences exist between neonatal and infant osteoarticular infections.
  • Further research is needed to enhance diagnostic accuracy and treatment strategies for these distinct pediatric populations.
Abstract

Keywords:
Clinical characteristicsInfantsNeonatesOsteomyelitisSeptic arthritis

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