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Association between body roundness index and prevalence of kidney stone in the U.S: a study based on the NHANES
Xike Mao1,2,3, Yuehan Yang1,2,3, Junping Yang4
1Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China.
Objective:
This study aimed to evaluate the potential association between the body roundness index (BRI) and kidney stone prevalence in adults in the United States.
Methods:
A cohort of participants from the National Health and Nutrition Examination Survey (NHANES) database spanning 2007-2018 were gathered for analysis. Logistic regression analyses, subgroup assessments, and calculations were employed to examine the potential link between BRI and kidney stone prevalence.
Results:
The study included 30,990 participants aged > 20 years, of which 2,891 declared a kidney stone history. After modulating all relevant confounding factors, each unit increase in the BRI was linked to a 65% increase in kidney stone prevalence (OR = 1.65, 95% CI: 1.47, 1.85). Sensitivity analyses conducted by categorizing the BRI into three groups revealed a 59% increase in kidney stone prevalence in the highest tertile BRI group compared to the lowest one (OR = 1.59, 95% CI: 1.42, 1.79). Furthermore, dose-response curves depicted a positive near-linear correlation between the BRI and the risk of kidney stone prevalence.
Conclusion:
These findings suggest a clinically noteworthy positive correlation between higher BRI values and kidney stone prevalence among the studied US adult population. However, it is essential to acknowledge that the observed relationship does not establish a causal link.
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