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Related Concept Videos

Disturbances in Heart Rhythm01:28

Disturbances in Heart Rhythm

947
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
947
Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

918
Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
918
ECG Interpretation of Arrhythmias I: Sinus Arrhythmias01:16

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias

213
Arrhythmias are disturbances in the heart's rhythm that lead to abnormal heartbeats. These irregularities can originate from different parts of the heart and are classified based on their origin and nature.
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...
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Related Experiment Video

Updated: Jun 28, 2025

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
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Post-stroke arrhythmia could be a potential predictor for post-stroke depression.

Tao Xu1, Fangying Dong1,2, Muhua Zhang1

  • 1Department of Cardiology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Shangcheng Avenue N1#, Yiwu, Zhejiang, China.

Scientific Reports
|April 20, 2024
PubMed
Summary

Post-stroke arrhythmia, particularly newly-detected or symptomatic types, may predict post-stroke depression (PSD). Managing arrhythmia can reduce PSD prevalence and severity.

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Area of Science:

  • Neurology
  • Cardiology
  • Psychiatry

Background:

  • Post-stroke depression (PSD) arises from complex factors affecting cognition, mood, and autonomic function.
  • Post-stroke arrhythmia, a common stroke-heart syndrome, shares potential pathogenic links with PSD.
  • The precise mechanisms linking these conditions remain unclear.

Purpose of the Study:

  • To investigate if post-stroke arrhythmia serves as an early indicator for PSD.
  • To determine the association between different types of post-stroke arrhythmia and PSD.
  • To explore the impact of arrhythmia control on PSD.

Main Methods:

  • Patients with first-ever ischemic stroke were enrolled.
  • Arrhythmia presence, symptoms, and treatment were recorded.
  • Patients were assessed for PSD and arrhythmia severity at 3-month follow-up using the Hamilton Depression Scale (HAMD).
  • Logistic regression identified predictors of PSD.

Main Results:

  • Higher prevalence of post-stroke arrhythmia, especially newly-detected, symptomatic, and poorly controlled types, was observed in patients with PSD.
  • Within the PSD group, patients with arrhythmia showed higher HAMD scores.
  • Newly-detected, symptomatic, and poorly controlled arrhythmias were independent predictors of PSD.

Conclusions:

  • Newly-detected and symptomatic post-stroke arrhythmias can be early predictors of PSD.
  • Effective management of post-stroke arrhythmia is associated with a reduced incidence and severity of PSD.