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Updated: May 11, 2026

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Published on: June 20, 2010
Structure-function relationship and biological activity of polysaccharides from mulberry leaves: A review
Yexian Hu1, Yan Zhang1, Xiaoao Cui1
1College of Biology, Food & Environment, Hefei University, Hefei 230601, PR China.
Abstract:
Mulberry (Latin name "Morus alba L.") is a perennial deciduous tree in the family of Moraceae, widely distributed around the world. In China, mulberry is mainly distributed in the south and the Yangtze River basin. Its leaves can be harvested 3-6 times a year, which has a great resource advantage. Mulberry leaves are regarded as the homology of medicine and food traditional Chinese medicine (TCM). Polysaccharides, as its main active ingredients, have various effects, such as antioxidant, hypoglycemic, hepatoprotective, and immunomodulatory. This review summarizes the research progress in the extraction, purification, structural characterization, and structure-function relationship of polysaccharides from mulberry leaves in the last decade, hoping to provide a reference for the subsequent development and market application of polysaccharides from mulberry leaves.
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