Related Experiment Video

Updated: Jun 28, 2025

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
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USP19 regulates DNA methylation damage repair and confers temozolomide resistance through MGMT stabilization

Jiaqi Liu1,2, Kaikai Wang3, Qian Zhu4

  • 1Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

CNS Neuroscience & Therapeutics
|April 22, 2024
PubMed
Abstract

Keywords:
MGMTdeubiquitinationglioblastomatemozolomide resistenceusp19

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