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Mechanical thrombectomy for middle cerebral artery M2 occlusions
Leyla Ramazanoglu1, Kalyoncu Isil Aslan1, Yilmaz Onal2
1Department of Neurology, University of Health Sciences Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey.
Acta Radiologica (Stockholm, Sweden : 1987)
|April 22, 2024
Summary
Mechanical thrombectomy (MT) is safe and effective for acute ischemic stroke (AIS) M2 occlusions. Treatment modality and anatomical location did not significantly impact 90-day prognosis or mortality in this study.
Area of Science:
- Neurology
- Interventional Neurology
- Stroke Medicine
Background:
- Mechanical thrombectomy (MT) is established for proximal large vessel occlusion in acute ischemic stroke (AIS).
- Endovascular treatment (EVT) for M2 occlusions in AIS is under active clinical investigation.
Purpose of the Study:
- To evaluate outcomes of M2 occlusions based on treatment strategy.
- To compare results between superior and inferior M2 branch occlusions.
Main Methods:
- Retrospective analysis of 113 consecutive M2 occlusions treated with EVT.
- Patients categorized into: MT alone, intravenous thrombolysis plus MT (IVT+MT), and IVT alone.
- Primary outcomes: 90-day functional prognosis (mRS 0-2) and mortality (mRS 6).
Main Results:
- Mechanical thrombectomy (MT) was used in 48.7% of cases.
- Bridging IVT with MT occurred in 37.2%, and IVT alone in 14.2%.
- No significant differences in 90-day prognosis or mortality were observed across treatment groups or between M2 superior/inferior branches.
Conclusions:
- Mechanical thrombectomy (MT) demonstrates safety and efficacy for M2 occlusions.
- Treatment modality and anatomical location did not significantly affect outcomes in this cohort.
