Related Experiment Video
Updated: Aug 19, 2026
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Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
Published on: March 14, 2011
Blocking of mononuclear cell activation by lonazolac
International Journal of Tissue Reactions
|January 1, 1985
Abstract:
The immunological effect of lonazolac on mononuclear cell activation has been investigated using the indirect Leukocyte Adherence Inhibition Test in Arthritis. Under these conditions, the mononuclear cell response to a synovial stimulus can be abolished by very low concentrations of lonazolac, a new nonsteroidal antiinflammatory drug. This blockade can be completely released by the addition of prostaglandin E2. Lonazolac appears therefore as an agent able in addition to modulate the immune response.
