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Related Experiment Video

Updated: Jun 28, 2025

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Pulse-echo ultrasound attenuation tomography.

Naiara Korta Martiartu¹, Parisa Salemi Yolgunlu¹, Martin Frenz¹

¹Institute of Applied Physics, University of Bern, Sidlerstrasse 5, 3012 Bern, Switzerland.

Physics in Medicine and Biology

|April 22, 2024

Summary

This summary is machine-generated.

This study introduces a novel 2D ultrasound imaging technique for precise tissue attenuation mapping. The method utilizes steered emissions and cross-correlations to accurately visualize spatial variations in tissue attenuation.

Keywords:

attenuation imaging inverse problems pulse-echo ultrasound tissue characterization ultrasound tomography

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Area of Science:

Medical Imaging
Biomedical Engineering
Acoustics

Background:

Accurate tissue property characterization is crucial for medical diagnostics.
Current ultrasound attenuation imaging methods have limitations in spatial resolution and accuracy.
Spatial variations in tissue attenuation are important indicators of tissue health and disease.

Purpose of the Study:

To develop and validate a fully two-dimensional (2D) attenuation imaging technique for pulse-echo ultrasound systems.
To overcome the limitations of line-by-line acquisition methods by using steered emissions for improved spatial resolution.
To enable accurate mapping of spatial variations in tissue attenuation properties.

Main Methods:

A novel 2D attenuation imaging technique using steered emissions in pulse-echo ultrasound.
Computation of normalized cross-correlations between beamformed images from different steering angles.
Formulation and efficient solution of a linear tomographic problem using Tikhonov-regularized least-squares.

Main Results:

The technique was validated using numerical simulations and experimental phantom studies.
Demonstrated accurate resolution of lateral variations in tissue attenuation.
Showed robustness and accuracy in media with heterogeneous echogenicity.

Conclusions:

The developed 2D ultrasound attenuation imaging technique offers superior spatial resolution compared to existing methods.
This method accurately characterizes spatial variations in tissue attenuation, even in complex media.
Potential for integration with speed-of-sound imaging for multi-modal ultrasound tomography.