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PDX Models in Theranostic Applications: Generation and Screening for B Cell Lymphoma of Human Origin
Shayla Shmuel1, Sébastien Monette2, Dina Ibrahim1
1Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Molecular Imaging and Biology
|April 22, 2024
Abstract:
This MIB guide briefly summarizes the generation of patient-derived xenografts (PDXs) and highlights the importance of validating PDX models for the presence of B cell lymphoma of human origin before their use in radiotheranostic applications. The use of this protocol will allow researchers to learn different methods for screening PDX models for Epstein-Barr virus (EBV)-infected B cell lymphoma.
