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Updated: Jun 28, 2025

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Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
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[Intensive exposure treatment for obsessive compulsive disorder in old age.]
Tijdschrift Voor Psychiatrie
|April 23, 2024
Summary
Older adults with obsessive compulsive disorder (OCD) can achieve remission with intensive exposure and response prevention therapy. This treatment also resolved comorbid depressive symptoms, demonstrating successful intervention for long-standing OCD.
Area of Science:
- Geriatric Psychiatry
- Clinical Psychology
- Neuroscience
Background:
- Obsessive compulsive disorder (OCD) typically emerges in younger individuals and often follows a chronic course.
- Limited research exists on treating OCD in older adults, contributing to therapeutic nihilism.
- Comorbid conditions, such as depression, can complicate OCD diagnosis and treatment in the elderly.
Observation:
- A 72-year-old male with lifelong OCD symptoms, previously treated only for recurrent depressive disorder.
- The patient received a brief, intensive exposure and response prevention (ERP) therapy over two weeks.
- OCD and depressive symptoms achieved full remission, allowing discontinuation of all psychotropic medications.
Findings:
- Short-term, intensive ERP was effective in treating long-standing OCD in an older adult.
- Successful treatment of OCD led to the remission of comorbid depressive symptoms.
- Medication was successfully withdrawn following the ERP intervention.
Implications:
- Comorbid depression can mask or lead to undertreatment of OCD in older populations.
- Effective treatment options exist for long-standing OCD in older adults, challenging therapeutic nihilism.
- Intensive ERP is a viable and potent therapeutic approach for geriatric OCD patients.
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