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DNA-affinity-purified Chip DAP-chip Method to Determine Gene Targets for Bacterial Two component Regulatory Systems
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A comprehensive analysis of pneumococcal two-component system regulatory networks

Jens Sivkær Pettersen1, Flemming Damgaard Nielsen1,2, Patrick Rosendahl Andreassen3

  • 1Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.

NAR Genomics and Bioinformatics
|April 23, 2024
PubMed
Summary

This study maps bacterial two-component systems in Streptococcus pneumoniae, revealing key regulatory networks. Novel bioinformatics identified and validated genes controlled by these systems, aiding understanding of pneumococcal pathogenicity.

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