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Tissue reactions to two root canal sealers containing formaldehyde
Oral Surgery, Oral Medicine, and Oral Pathology
|December 1, 1985
Summary
This study investigated tissue reactions to root canal sealers Endomethasone and N2 in dogs. Formaldehyde-containing sealers like N2 caused significant tooth ankylosis and resorption, questioning their clinical use.
Area of Science:
- Endodontics
- Dental Materials Science
- Veterinary Dentistry
Background:
- Root canal sealers are crucial for successful endodontic treatment.
- Previous sealers have raised concerns regarding biocompatibility and long-term effects.
- Understanding tissue response to sealers is vital for patient safety.
Purpose of the Study:
- To evaluate the tissue reaction to Endomethasone and N2 root canal sealers.
- To assess the potential for ankylosis and resorption associated with these sealers.
- To determine the clinical suitability of formaldehyde-containing root canal sealers.
Main Methods:
- Histological examination of premolar teeth in dogs following root canal filling.
- Comparison of tissue response between Endomethasone and N2 sealers.
- Assessment of periapical inflammation, ankylosis, and root resorption.
Main Results:
- Frequent periapical inflammation was observed with both sealers.
- Universal ankylosis and significant root resorption were noted in teeth filled with N2.
- One tooth filled with Endomethasone also showed ankylosis and resorption.
Conclusions:
- The use of N2 and Endomethasone root canal sealers is not supported due to adverse tissue reactions.
- Formaldehyde-containing sealers can lead to severe complications like ankylosis and resorption.
- Further research into safer root canal sealing materials is warranted.