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A Fluorescent Probe for Hg2+ Specific Recognition Based on Xanthene and its Application in Food Detection and Cell
Chenglu Zhang1, Shiru Nie2, Chang Liu2
1School of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian, Liaoning, 116029, China. zhangchenglu@lnnu.edu.cn.
Abstract:
The mercury-loving unit aminothiourea was introduced into the xanthene fluorophore to synthesized the probe molecule NXH. NXH has a specific response to Hg2+, and with the addition of (0 ~ 50 µM) Hg2+, the fluorescence intensity of the probe solution was quenched from 2352 a.u. to about 308 a.u. NXH exhibited excellent detection performance of high sensitivity (LOD = 96.3 nM), real-time response (105 s), wide pH range (2.1 ~ 9.3), and strong anti-interference ability for Hg2+. At the same time, NXH has wide range of applications for Hg2+ detection, which can fluorescence imaging of Hg2+ in Hela cells and tea samples, and can also be made into Hg2+ detection test paper.
