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Modifiable risk factors that may be addressed in routine care to prevent progression to and extension of
Andi Orlowski1,2, Jack Ettinger3, Alex Bottle2
1Health Economics Unit, London, UK andi.orlowski@nhs.net.
BMJ Open Respiratory Research
|April 23, 2024
Summary
Patients with chronic obstructive pulmonary disease (COPD) often have multiple co-occurring conditions (multimorbidity). Addressing these prevalent, often preventable, conditions can improve quality of life and reduce healthcare costs.
Area of Science:
- Pulmonary Medicine
- Public Health
- Epidemiology
Background:
- Chronic obstructive pulmonary disease (COPD) is a complex multisystem condition.
- Patients with COPD frequently experience multiple co-occurring diseases (multimorbidity).
Purpose of the Study:
- To explore multimorbidity patterns in COPD patients.
- To inform intervention strategies for reducing healthcare costs and improving patient quality of life.
Main Methods:
- Systematic literature review of observational and comparative studies up to February 2022.
- Included 29 studies analyzing risk factors for multimorbidity in COPD, pulmonary emphysema, or chronic bronchitis.
Main Results:
- COPD patients exhibit significantly higher rates of multimorbidity, with up to ten times more disorders than non-COPD individuals.
- Commonly associated conditions include cardiovascular, metabolic, asthma, musculoskeletal, and psychiatric disorders.
- Low socioeconomic status is a key risk factor; polypharmacy and inappropriate medication use increase adverse event risk.
Conclusions:
- A substantial portion of multimorbidity in COPD is preventable or modifiable.
- Proactive, multidisciplinary prevention and management strategies are crucial for reducing the burden of care.
Keywords:
COPD epidemiology
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