Preoperative MRSA screening using a simple questionnaire prior elective total joint replacement

Fidelius Von Rehlingen-Prinz1,2, Michael Röhrs1, Nemandra Sandiford1

  • 1Department of Orthopedic Surgery, Helios ENDO-Klinik Hamburg, Holstenstrasse 2, 22767, Hamburg, Germany.

Abstract

Insights

A standardized questionnaire effectively identifies patients at high risk for MRSA colonization before joint replacement surgery. This targeted screening reduces costs and may lower the risk of periprosthetic joint infection.

Area of Science:

  • Orthopedic Surgery
  • Infectious Disease Epidemiology
  • Healthcare Management

Background:

  • Methicillin-resistant Staphylococcus aureus (MRSA) colonization poses a risk for surgical site infections, particularly in joint replacement procedures.
  • Standardized protocols for preoperative identification of MRSA colonization are crucial for patient management.
  • Evaluating the effectiveness and cost-efficiency of screening methods is essential.

Purpose of the Study:

  • To assess a standardized protocol for preoperative MRSA colonization identification in patients undergoing hip and knee replacements.
  • To evaluate the efficacy of a risk-assessment questionnaire in identifying high-risk patients for MRSA screening.
  • To analyze the cost savings associated with targeted MRSA testing versus universal screening.

Main Methods:

  • A cohort of 37,745 patients awaiting elective joint replacement were assessed using a standardized questionnaire.
  • Questionnaire data was analyzed to identify effective questions for MRSA risk stratification.
  • The impact of comorbidities and Charlson Comorbidity Index on MRSA colonization was evaluated.
  • Cost analysis compared targeted testing with universal screening.

Main Results:

  • Of 37,745 patients, 8,057 (21.3%) were screened, with 65 (0.81%) testing positive for MRSA.
  • Key indicators for MRSA colonization included recent hospitalization (47.7%) and prior MRSA history (44.6%).
  • Targeted testing resulted in a 79% cost reduction compared to universal screening.

Conclusions:

  • A simple, standardized questionnaire is a valuable tool for preoperative MRSA screening.
  • The questionnaire effectively identifies high-risk patients for MRSA colonization.
  • This targeted approach may reduce the incidence of periprosthetic joint infection and related complications.

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