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Related Experiment Video

Updated: Jun 28, 2025

Author Spotlight: Integrating Mechanical and Biological Analysis in Tendinopathy Research

Author Spotlight: Integrating Mechanical and Biological Analysis in Tendinopathy Research

Published on: March 1, 2024

An Isometric and Functionally Based 4-Stage Progressive Loading Program in Achilles Tendinopathy: A 12-Month Pilot

Thøger Persson Krogh^1,2,3, Thomas Theis Jensen², Merete Nørgaard Madsen⁴

¹Diagnostic Centre, University Research Clinic for Innovative Patient Pathways, Silkeborg Regional Hospital, Silkeborg, Denmark.

Translational Sports Medicine

|April 24, 2024

Summary

This summary is machine-generated.

This pilot study shows a new home-based Achilles tendinopathy (AT) rehabilitation program using isometric exercises and progressive loading is feasible and safe. Athletes experienced significant improvements in pain and tendon structure, suggesting potential for future trials.

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Last Updated: Jun 28, 2025

Author Spotlight: Integrating Mechanical and Biological Analysis in Tendinopathy Research

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Ex vivo Mechanical Loading of Tendon

Ex vivo Mechanical Loading of Tendon

Published on: May 28, 2007

Author Spotlight: Effectiveness of Extracorporeal Shockwave Therapy in Achilles Tendinopathy Treatment

Author Spotlight: Effectiveness of Extracorporeal Shockwave Therapy in Achilles Tendinopathy Treatment

Published on: August 2, 2024

Area of Science:

Sports Medicine
Musculoskeletal Rehabilitation
Orthopedic Surgery

Background:

Achilles tendinopathy (AT) presents a significant clinical challenge in musculoskeletal rehabilitation.
Current management strategies for AT often yield suboptimal outcomes for athletes.
A novel, home-based rehabilitation approach is needed to address these limitations.

Purpose of the Study:

To evaluate the feasibility and safety of a new 4-stage, home-based rehabilitation program for Achilles tendinopathy (AT).
To assess preliminary clinical improvements, including pain and functional scores, in athletes with chronic AT.
To gather data supporting the design of a future randomized controlled trial (RCT) for this AT intervention.

Main Methods:

A pilot study involving ten recreational athletes diagnosed with chronic midportion Achilles tendinopathy (AT).
Implementation of a 4-stage home-based rehabilitation program incorporating isometric exercises and progressive loading.
Primary outcome: VISA-A score at 1, 2, 3, 6, and 12 months; Secondary outcomes: Tenderness and ultrasonographic changes at 6 months.

Main Results:

Significant improvements in VISA-A scores were observed at 6 months (+26.9 points, P=0.004) and 12 months (+35.4 points, P=0.006).
Reduced tendon tenderness (P < 0.001) and decreased ultrasound measures of inflammation (Color Doppler activity reduced by 50%, P=0.023) and structural changes (hypoechoic area reduced from 29.1% to 8.5%, P=0.001) were noted.
High adherence and no safety issues confirmed the program's feasibility.

Conclusions:

The 4-stage home-based rehabilitation program, featuring isometric training and progressive loading, demonstrated significant improvements in athletes with Achilles tendinopathy (AT).
This approach proved feasible and safe, with high adherence rates among participants.
The positive outcomes warrant further investigation in a larger randomized controlled trial (RCT).