Related Experiment Video
Updated: Jun 28, 2025

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
How do social networks, perception of social isolation, and loneliness affect depressive symptoms among Japanese
Natsuho Kushibiki1, Miyuki Aiba2, Haruhiko Midorikawa3
1Department of Disaster and Community Psychiatry, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Objective:
This study aims to elucidate the complex relationship among social isolation, loneliness, and perception of social isolation and its influence on depressive symptoms by evaluating a hypothetical model. This understanding is essential for the formulation of effective intervention strategies.
Methods:
We conducted an online survey on Japanese adults (N = 3,315) and used the six-item Lubben Social Network Scale to assess the size of their social networks. We employed a single question to gauge their perception of social isolation. Loneliness was assessed using the three-item UCLA Loneliness Scale, and depressive symptoms were examined using the Patient Health Questionnaire-9. Structural equation modeling was employed to test the hypothesized model.
Results:
The final model demonstrated satisfactory fit with data (χ2 (1) = 3.73; not significant; RMSEA = 0.03; CFI = 1.00; TLI = 1.00). The size of social network demonstrated a weak negative path to loneliness and depressive symptoms (β = -.13 to -.04). Notably, a strong positive association existed between perception of social isolation and loneliness (β = .66) and depressive symptoms (β = .27). Additionally, a significant positive relationship was found between loneliness and depressive symptoms (β = .40). Mediation analysis indicated that perception of social isolation and loneliness significantly intensified the relationships between social networks and depressive symptoms.
Conclusions:
Results indicate that interventions of psychological approaches, such as cognitive-behavioral therapy, are effective in reducing the perception of social isolation and loneliness, which may lead to the prevention of depressive symptoms. Future longitudinal studies are expected to refine and strengthen the proposed model.
More Related Videos
Related Concept Videos
Relationship Formation
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Erikson's Theory on Socioemotional Development during Adulthood
Intimacy Versus Isolation in Early Adulthood
Individuals in early...
Depressive Disorders: MDD and Dysthymia
Theory of Romantic Attachment in Adulthood
Self-Discrepancy Theory

